Always keep in mind if you push a given weight out a barrel to a given velocity the "Average" pressure over the entire length of the barrel is virtually identical. One does not truly raise or lower it, just re-arranges it.

As long as the peak pressure does not exceed the limits of the chamber walls, the overall ballistics of the load is of more concern everywhere else.
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Miller/TN
I Didn't Say Everything I Said, Yogi Berra