If they can be made as strong as a modern homogenous steel barrel, they would still be a custom or very limited market item. As such, both the specialized process of damascus manufacture and the low production and high hand work to fit them/make them for whoever's double (one guy wants some Parker barrels, another wants some Lefever barrels, etc), would be all a custom type of work. That means you're paying for labor. The price of such a set of barrels could be pretty steamy. I'm guessing just to make wages for a couple guys, it'd cost in the area of $5-7k not including any development amortization of the damascus manufacture.

So, it starts to make the priciest shells to shoot a damascus gun seem cheap (IMO).

Start reloading for one and it levels the field on ammo costs against modern guns.

Frankly, I prefer to mix up my shooting with modern guns and vintage guns. Both offer me something.