Putting this here because more single shots use peeps/irons than most others.

https://www.nytimes.com/2021/12/14/..._bandit-all-surfaces_filter_new_arm_10_1

Can't read it, they are trying to extort $$.

New Eye Drops Offer an Alternative to Reading Glasses

Vuity, a once-a-day treatment that can help users see up close without affecting their long-range vision, went on the market Thursday after being approved by the F.D.A. in October.
Credit...iStock/Getty Images

By Melinda Wenner Moyer
Dec. 14, 2021, 12:35 p.m. ET

An eye drop that improves close-range vision could make misplaced reading glasses less of an inconvenience for many of the 128 million Americans who suffer from age-related deficits in near vision. Vuity, which became available by prescription on Thursday, is a once-a-day treatment that can help users see up close without affecting their long-range vision.

“For anybody who doesn’t want to fiddle with reading glasses, this might be a really helpful alternative,” said Dr. Scott M. MacRae, an ophthalmologist at the University of Rochester’s Center for Visual Science. Dr. MacRae was not involved in the clinical trials for the drug, which was approved by the U.S. Food and Drug Administration in late October.

Nearly 90 percent of U.S. adults over 45 have problems with close-range vision, a condition known as presbyopia that typically worsens over time. To focus on close objects, the eye’s lens must change shape, yet it becomes less flexible as people age, making this process difficult. “Your ability to zoom in decreases,” Dr. MacRae said.

People who suffer from presbyopia often find they need to hold a book at arm’s length or turn on a bright light to read it, said Dr. George O. Waring IV, an ophthalmologist and the medical director of the Waring Vision Institute in Mt. Pleasant, S.C., who led Vuity’s clinical trials for the pharmaceutical company Allergan. Typically, eye doctors recommend that people with presbyopia wear over-the-counter or prescription reading glasses when they need to see up close, but Vuity may also be an option for them, he said.

Vuity improves near vision by constricting the size of the pupil. “It makes the pupil small, creating what we call a pinhole effect,” that way reducing the amount of peripheral light that passes through the eye that can make it hard to focus, said Dr. Stephen Orlin, an ophthalmologist at the University of Pennsylvania Perelman School of Medicine.
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Vuity’s active ingredient is a drug called pilocarpine, and it is not a new medication. It’s actually “one of the oldest drops that we have in ophthalmology,” Dr. Orlin said. It has been used for decades to treat glaucoma, a condition characterized by damage to the optic nerve. Although Vuity is the first product of its kind to treat presbyopia, at least nine similar eye drop products are in clinical development to treat presbyopia and may be available in the future, Dr. Waring said.

Dr. Waring and his colleagues presented the results of their Phase 3 clinical trials, which have not yet been published in a peer-reviewed journal, at the 2021 annual meeting of the American Society of Cataract and Refractive Surgery in July. A single Vuity drop in each eye improved trial subjects’ close-range vision for six hours and improved their intermediate vision — important for computer work — for 10 hours.

Vuity’s benefit over reading glasses is that it does not impair distance vision like reading glasses do. Usually, when a person stops reading to do something else, they need to remove their reading glasses to see around them properly. “That’s the good part about this — the drops don’t really affect distance vision under normal daylight conditions,” Dr. MacRae said.

Dr. MacRae also noted that Vuity will work best for people who have only mild to moderate presbyopia, which probably means people between the ages of 45 and 55. Older individuals with more serious presbyopia may find that the eye drops do not improve their near vision enough to make a difference.


Vuity does not correct regular nearsightedness, farsightedness or astigmatism — it improves only the age-related deficits in close-range vision. So people with other eye errors will want to continue wearing glasses or contact lenses even if they also use Vuity, Dr. MacRae noted.

And the drops are not meant to replace reading glasses entirely, Dr. Waring said. People with presbyopia will probably want to own reading glasses, too, but Vuity may reduce the amount of time they need to wear them.

“For some people, it’s going to work great,” Dr. MacRae said.

Vuity is not typically covered by health or vision insurance, and Dr. Waring said it might cost around $80 per 30-day supply.

Although the clinical trials did not report any serious side effects, 14.9 percent of subjects who took Vuity reported mild headaches, compared with 7 percent of subjects who took placebo drops. Up to 5 percent of subjects taking Vuity reported other side effects such as eye redness, blurred vision, eye pain, visual impairment, eye irritation and an increased production of tears.

Because the eye drops reduce pupil size, they also make it harder to see in the dark, so they are not recommended for people who drive at night or need to see well in low light for other reasons, Dr. Waring said.

Sharp focus on the iron sights is not the only prerequisite to good shooting with "irons". Good shooting with iron sights also includes the ability to shift focus from the front sight to the bullseye/target a few times, very rapidly, then focusing on the front sight until trigger break. How would this affect the ability to do that? Just curious because I may be someone who could benefit.

There are better solutions that accomplishes the same thing that this drug does, and has a ~1.5 centuries track record.

OK, let's not read too much into my original post and dissect it.

For someone my age, seeing iron sights means wearing readers, which then screw up distance vision. This may alleviate that.

I had 3 rounds of cast bullet loads that I wanted to use up in my open sighted 1886 model .33 WCF.

I stuck up a zero target on the backing board at 100 yards and went back to the bench.

With my contact lenses in I found that whilst I could see the aiming mark on the zero target I could not focus the foresight bead.

I put on my reading glasses. Viola! I could see the bead, BUT not the aiming mark.

I knew where the zero target was on the backing board, wanted to use up those three loads, so fired them off at where I remembered putting it.

When I retrieved it I had shot a 2 inch group.

Conclusion;- My memory is lasting better than my eye sight.

I need glasses to see distance but do not need readers. As I have aged I now struggle to see the rear sight clearly with my glasses on, no issue at all seeing sights without glasses but then the target is blurry. Not sure if the drops will help or not but worth talking to my eye doctor about it.

I vote red dot...Trijicon MRO or RMR...skip the drops.

Years ago my ophthalmologist set up my contact prescription right eye distance, left eye reading. It works great for shotgunning, but have recently discovered when I got back into pistol shooting I can’t see the sights very well with my right eye and now shoot my pistol targets with my left eye. It actually works well.

Similar condition here. I normally use 2.75 reading glasses, but for iron sight use and with pistols I put on 1.00 or 1.25's and they bring the sights into focus with the bullseye still very well defined, at least well enough to hit it efficiently.

And they are?

Well, my solution for seeing the shallow V, the front bead, and the target using my Alexander Henry was to get a pair of Beretta shooting glasses (cheap and have no frame to complicate things) and put small Lyman stick-on or Gehmann clamp-on peep on them. The Gehmann is also adjustable for size of peep hole.

Basically wht HalfaDouble said. The drug forces you into a constricted lens. A peep sight/tang sight/stick-on-glasses aperture does the same thing without drugs and without forcing you to live with the constricted lens all the time, which is a big downside.

Aperture sights can be fitted with weak diopters or you can put on on a pair of inexpensive glasses that have a weak (+0.5 or +0.75 diopter) that does the same thing.

Halfadouble, were can I find the Gehmann adjustable? I've not heard of that particular one.

This is the main reason for the tip up aperture sights in the tang of some German combination guns. A discussion of these sights may be found in an old thread, either here or at the GGCA forum. Old eyes have been a problem ever since we started hunting with sights on the guns.
Mike

FYI - If you want to experiment with a good and inexpensive solution that lets me see a front sight clearly at about 31” out these are the bomb:

https://www.amazon.com/gp/aw/d/B00KSJNLO0?psc=1&ref=ppx_pop_mob_b_asin_title

Works on long guns and pistols…doesn’t make me a better shot but eliminates fuzzy front sight.

(Get the 1 diopter)

Here you go Brent: http://www.champchoice.com/store/Main.aspx?p=ItemDetailOptions&item=390
Dave, I'm not sure what those glasses would do to a 200 meter target since a 1 diopter lens focuses at 1 meter distance. The front sight would be great but is the target going to blob at 200?

I misspoke when I said, earlier, "iron sights", I meant open sights. In the crowd I used to run with and compete with that meant notch and post (open) iron sights. Of course, iron sights can mean aperture sights. I competed many years with both, and understand how a rear aperture can help aging eyes to clarify the front sight and the bullseye. I use, and have used, a Merit adjustable aperture rear for over 30 years, with much success.

So, back to my question, which I will reword.............. how can these eyedrops help aging eyes to shift focus from the front POST to the rear NOTCH, and back and forth, until settling on the front sight and breaking the sear?

thanks Halfdouble. I have one headed my way right now!

The drugs won't help you focus back and forth, neither will the aperture, but both will increase depth of field so less focusing is necessary.

Different games have different rules. So, this may not be legal in some games, but is in others. It is also perfect for hunting with the flip-up feature, similar to what I"m using now.