I have seen litter mates that were as different as night and day. You are going to need the assistance of the breeder, who should know what you want before the litter hits the ground.
With the Setters I have had a choice on, I bring a fishing pole with a pheasant wing, and watch the pups reaction. After a bit of that, I plop my butt down and figure out which pup likes me. Totally unscientific, but, I have had a few good dogs, and at least one great one.
Might as well mention, you dont always win with a dog, temperament, health, intelligence. I believe having kids around from puppy on will be a plus, regardless.
Best of luck. Few days in life are as good as new puppy day.
Best,
Ted