It's a personal choice and often debated.

I carry my Hammer guns cocked cartridges in the chambers gun open. Same way I carry a Hammerless gun . Hammer gun you don't have to take the safety off when you close it.

Personally very uncomfortable in the field with someone who's gun is loaded closed and dependent on the safety. Some use good muzzle direction discipline even so open gun is a 2nd level of safety. Many SxS guns mechanical safety is not all that reliable. If she's open she can't go off.

Boats