I shot over 3,000 patterns looking for ultimate long range performance back in the 80s. I do not fault Dr. Jones' efforts, and I apologize if I sound high handed, but other than as a mathematical exercise, I didn't "get it" is the only way I can put it. Analyzing patterns with small shot at Sporting ranges struck me sort of like optimizing a Chevy Impala to circulate LeMans at 60 miles an hour, versus tweaking a Ferrari or Porsche to hit 200 on the straight and average well over a 100. I make no claims to being an accomplished statistician or mathematician. I did find that when comparing the effect of a variable I did get down to comparing 10 shot averages the get conclusive at the end of each trial.
I was quite satisfied with my results, but I am still rather mystified at how George Diggweed manages to do a lot of what he does, with what he uses. That guy just amazes me.