I was born and raised in PA and plan to retire here when the time comes. There is excellent hunting and fishing and the state is (at least for the time being) relatively gun friendly.
If you are willing to live out in the country (and I am), costs are pretty low. If you pick the right locations, there is good health care and plenty of culture (PA has an excellent state university system with plenty of interesting stuff going on).
There are negatives - the urban areas are all a mess, every one of them. The industrial base is gone and the state isn't business friendly (not a particular concern if you are retired and aren't looking for a job) and its population is aging. I suspect it will have serious financial problems in the future.
However, negatives notwithstanding, I expect to finish out my days here, hopefully with either a fly rod or a shotgun in hand or a pack on my back walking the thousands of miles of public trails.
Time will tell.
Exactly why I retired here from Florida. Getting used to the weather was tough, but fall was spectacular! Very gun friendly. During the winter I went to a gun show every weekend. Love it here.