"Is anybody else a little itchy about the idea of a .25 Krag in a Lowall?"

If you're talking about an original Winchester Low Wall, I think the action isn't strong enough for it. Maybe the modern low wall would work.

I have a Highwall action that I have contemplated barreling to 25 Krag, but I don't want any more wildcats. I'm thinking a 7X57R or a 6.5X57R would be nice.