"...they could get an infection" LOL, good one Greg.
C'mon Greg, shot coming out of a 410 barrel is going the same velocity as out of a 12ga. The 25acp analogy doesn't hold up. In the case of the 25acp, the projectile doesn't have the energy required to penetrate the distance needed. That's not the case for the 410. Same size shot going the same velocity as a 12ga. in most cases.
It's more a case of taking a longer than usual shot with whatever weapon of choice, whether handgun, rifle, or bow. A reduced angular error that is tolerable, that's all.
If game in the bag is the goal, it cuts against all those that say they don't need lots of game in the bag to enjoy. If zero wounded game is the only acceptable outcome, hunting with any shotgun is not for that person.
