I'm aware of a catastophic failure/blow up that occured with a factory round that had been rolling back & forth on a ranch truck's dash for some indeterminate, but lengthy, period of time and had also been repeatedly heated to 'hot to the touch' temps from the same situation during the Texas afternoons. Good chance/probability(?) that the powder had become 'dust' and/or the burning rate deterrents had become negated.

Dif between burn & detonate[VoD] is the speed, ya know; i.e., fuse burns, Primacord detonates.

Not saying that's what happened in the example depicted, rather it is an example of how a loaded cartridge could change.