While there are some good reminders on safety here, it's probably also a good idea to remember this: with the exception of those guns with intercepting sears--which are a definite minority, most of them sidelocks--about the only thing the safety guarantees is that you can't pull the trigger(s). If you stumble and fall, when presumably you would not have your finger on the trigger(s), a gun without intercepting sears is about as likely to discharge accidentally whether the safety is engaged or not. Not being a hammergun specialist in any way, shape or form, I can't comment on how likely a gun with the hammer down would be to fire as a result of a similar fall, but I do remember the old cowboy rule about keeping an empty chamber under the hammer in a Colt SAA.