How about a takedown switch-bbl in 17 HM2 or HMR, 22LR or 22WMR, 219 Zipper, 25-35, 7-30 Waters, 30-30 and 35/30-30? The RFs can be used with offset bores to allow the CF firing pin to strike the RF edge while the 30-30-size extractor will extract the RF cases adequately from the offset bore.
Joe
Your switching barrels why not switch trigger groups also and insert the correct one when needed; one for rimfire, one for rim fire magnum and one for centerfire. Then all you would have to do is keep all your centerfires with the same cartridge head.