My increasingly squishy brain has been contemplating these numbers with some concern but it should be noted that Sherman Bell's sequentially increasing load experiment did not blow out the chamber of a Parker VH Damascus until almost 30,000 psi - about 2 1/2 times Barlow's burst pressure. 'Zircon's' unpublished metallurgical examination DID show low cycle fatigue.
Our examination of the obstruction burst (a single high pressure event) did NOT show low cycle fatigue however.

We know the ejecta is moving before maximal pressure is reached in the absence of an obstruction