The 235, 270 and 300 grain bullets were said to all go to the same point of impact. Don't know if that was advertising hype or only applied to H & H rifles using Kynoch ammo. Never tried it myself. I do have a CZ in .375 and just load 235 grain bullets at a modest velocity and find it not unpleasant to shoot and both very accurate and effective on medium to large deer species. Lagopus.....